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28 Jan 2016 - 10:00

DuPont Nutrition & Health Confirms Appetite-Reducing Ability of Dietary Fiber

DuPont Nutrition & Health has collated convincing scientific evidence to support the appetite-suppressing effect of the dietary fiber Litesse® polydextrose, part of the DuPont™ Danisco® range, in two meta-analyses. Both have now been published in scientific journals.

The meta-analyses are the outcome of a systematic review of key studies that have investigated the impact of Litesse® consumption on calorie intake and subjective feelings of appetite.

Calorie consumption reduced by 5-15%

Summarizing the studies of calorie intake, the first meta-analysis concludes that the inclusion of 6.25-25g of Litesse® in a mid-morning snack reduces lunchtime calorie consumption by 5-15%.

“In addition, we have seen that this reduction in calorie intake is not compensated for during the rest of the day and may play a role in reducing total daily calorie intake significantly,” says Dr. Alvin Ibarra, senior scientist and member of the DuPont Nutrition & Health review team.

Impact on appetite

The meta-analysis of subjective appetite ratings found a similar positive effect of Litesse® polydextrose.

Dr Ibarra said: “This shows that Litesse® is able to reduce the desire to eat immediately after a meal which includes Litesse®. There is also a trend towards reduced hunger and increased satisfaction between meals after the consumption of Litesse®”. And he goes on to say: “This means that Litesse® represents a very exciting opportunity for our customers who wish to develop their weight management products with satiety enhancing and appetite reduction qualities. Our customer applying Litesse® to their own brands can now help consumers reduce their caloric consumption and help them meet their weight-management goals.”

A new methodology for measuring changes in appetite

During the review of the studies of appetite ratings, the biggest challenge was to make a meaningful comparison of results obtained from widely differing criteria. The DuPont scientific team met the challenge head on by developing a new methodology for estimating changes in appetite before and after a meal.

Dr Ibarra adds: “We are now using this new methodology to analyze the appetite rating results during the satiation and satiety periods with a positive acceptance from the scientific community.”

Publication in key journals

The meta-analyses of calorie intake and subjective feelings of appetite have been published in the peer-reviewed journal Appetite and a special Food and Appetite issue of Nutrients. The references are as follows:

Ibarra A, Astbury NM, Olli K, Alhoniemi E, Tiihonen K. Effects of Polydextrose on Different Levels of Energy Intake: A Systematic Review and Meta-Analysis. Appetite. 2015 Apr 1;87C:30-37. http://www.sciencedirect.com/science/article/pii/S0195666314006527

Ibarra A, Astbury NM, Olli K, Alhoniemi E, Tiihonen K. Effect of Polydextrose on Subjective Feelings of Appetite during the Satiation and Satiety Periods. A Systematic Review and Meta-Analysis. Nutrients. 2016. http://www.mdpi.com/2072-6643/8/1/45


DuPont™ Danisco® is the brand for a range of ingredients that help provide enhanced bioprotection, an improved nutritional profile, and better taste and texture with greater cost efficiency and lower environmental impact, meeting the needs of manufacturers of food and beverages, dietary supplements and pet food. Through the work of the global network of food scientists and technologists in DuPont, the Danisco® range is supported by a uniquely broad spectrum of know-how across applications and processing.

DuPont Nutrition & Health addresses the world’s challenges in food by offering a wide range of sustainable, bio-based ingredients and advanced molecular diagnostic solutions to provide safer, healthier and more nutritious food. Through close collaboration with customers, DuPont combines knowledge and experience with a passion for innovation to deliver unparalleled customer value to the marketplace. Follow us on LinkedIn.

DuPont (NYSE: DD) has been bringing world-class science and engineering to the global marketplace in the form of innovative products, materials, and services since 1802. The company believes that by collaborating with customers, governments, NGOs, and thought leaders we can help find solutions to such global challenges as providing enough healthy food for people everywhere, decreasing dependence on fossil fuels, and protecting life and the environment. For additional information about DuPont and its commitment to inclusive innovation, please visit www.dupont.com.

Richard Donovan
Richard Donovan
Communications Manager
+33 (0) 6 71 58 98 54
Paris, France