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07 Sep 2016 - 10:00

DuPont Study Confirms Anti-Caries Effect of Xylitol

New Findings to be Presented at the 2016 FDI Annual World Dental Congress on 7-10 September.

Scientific research at DuPont Nutrition & Health has found that the oral bacteria behind dental cavities are significantly reduced in the presence of xylitol. Conducted using the DuPont dental caries simulator, the study gives an improved understanding of results from previous clinical studies.

Xylitol is a naturally occurring sweetener with the taste and sweetness of sugar but just half the calories. The European Food Safety Authority (EFSA) has recognised the claim that xylitol chewing gum reduces the risk of caries in children.

Positive effect also in the presence of sucrose
Recently published in Archives of Oral Biology journal, the DuPont study evaluated the effect of sucrose and xylitol on Streptococcus mutans – one of the main species of bacteria responsible for dental caries.

Xylitol was shown to have a significant impact on the bacteria, also when tested in combination with sucrose. The xylitol used for the study was XIVIA® Xylitol from the DuPont™ Danisco® range.

Realistic results from dental simulator
“This in vitro study was the first to test the effect of xylitol on S. mutans using our in-house dental simulator,” says Krista Salli, M.Sc. scientist, DuPont Nutrition & Health in Kantvik, Finland.

“It is encouraging to see that the results closely reflect clinical findings. This is evidence that the oral environment created by our simulator is realistic and suitable for estimating the cariogenicity of food ingredients. This will help us understand the mechanism by which xylitol exerts in benefits.”

Presentation at 2016 FDI World Dental Congress
Previous studies have shown that xylitol reduces acidity in the mouth by raising the pH level; slows the ability of cariogenic bacteria to stick to teeth; and inhibits bacterial growth. EFSA has approved the following claim related to xylitol use: ‘100% xylitol chewing gum reduces the risk of plaque in children and plaque is a biomarker for dental caries’.

DuPont will present additional new findings from a second study using the dental simulator at the 2016 FDI World Dental Congress at 10-11am on 9 September in Pavilion 15, level 0, hall 0.F.

The published study entitled ‘Influence of sucrose and xylitol on an early Streptococcus mutans biofilm in a dental simulator’ is available online - please click here to view.

 

 

DuPont Nutrition & Health addresses the world’s challenges in food by offering a wide range of sustainable, bio-based ingredients and advanced molecular diagnostic solutions to provide safer, healthier and more nutritious food. Through close collaboration with customers, DuPont combines knowledge and experience with a passion for innovation to deliver unparalleled customer value to the marketplace. Follow us on LinkedIn.

DuPont (NYSE: DD) has been bringing world-class science and engineering to the global marketplace in the form of innovative products, materials, and services since 1802. The company believes that by collaborating with customers, governments, NGOs, and thought leaders we can help find solutions to such global challenges as providing enough healthy food for people everywhere, decreasing dependence on fossil fuels, and protecting life and the environment. For additional information about DuPont and its commitment to inclusive innovation, please visit www.dupont.com.

Aparecido Silveira
Senior Communications Specialist
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Reigate, United Kingdom