Use of GMMs in enzyme production

Production of enzymes often uses genetically modified microorganisms (GMMs). Because GMMs do not include genetically modified plants and animals, they are considered a subclass of genetically modified organisms (GMOs). It is important to understand that the enzymes are produced by the GMMs and are then extracted from them; enzymes are not living organisms.

We understand the importance of protecting human health and safety and maintaining the genetic integrity of our environment. Danisco uses only Class 1 GMMs in production. They are nontoxic and nonpathogenic, and are as safe for humans, animals, and the environment as the nontoxic, nonpathogenic host or parental strain. Our Class 1 GMMs have a proven history of safe use and/or have limited survival in nature. The sequences and functions for their inserted DNA are fully known, and they do not easily transfer DNA to other microorganisms.

Danisco also uses state-of-the-art technology and follows strict operational protocols to minimize release of GMMs into the environment.

All of our production is carried out in contained facilities. Our production process takes place in fermentation vessels and recovery equipment designed to keep the production organisms contained within them and the production facility.

The products are tested for the absence of the production organism during quality control and meet the specification of no detectable production organisms. This specification is followed for both GMMs and traditionally derived production organisms.

In accordance with local and national regulations waste containing our production organisms is treated before disposal at all sites. The treatment is according to validated practices in all but two sites, which will follow in 2006. The validated practices are re-evaluated regularly.

We are committed to full compliance with regulatory policies in all areas where we manufacture or deliver products. In addition, we work with legislators, regulators, and other stakeholders to assure that new governmental policies regarding biotechnology are appropriate to protect consumers and the environment.