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4 February 2004 - 00:00

"Safe" status for betaine

Betaine is now a GRAS (Generally Recognized As Safe) ingredient in the USA in selected applications.

Betaine has been used in human and animal nutrition for over 70 years as a methyl donor and osmolyte. It is now a GRAS ingredient (Generally Recognized As Safe) in the USA in selected applications supported by clinical and safety studies.

Several health benefits of betaine
There has been growing interest in betaine (also known as trimethylglycine, TMG) following published research that shows a link between elevated levels of serum homocysteine and cardiovascular disease, Alzheimer's and other metabolic disorders. Clinical studies show that betaine, a compound extracted from sugar beet molasses, can lower homocysteine levels.

In addition, betaine can improve liver and kidney function. It has been suggested that a deficiency in methyl donors, including betaine, can lead to incomplete DNA methylation with subsequent genetic instability, aging and cancer.

Finally, betaine protects against dehydration and other types of stress, and may even improve athletic performance. "The unique properties of betaine have stimulated clinical research around the world", stated Dr. Stuart Craig, Scientific and Regulatory Affairs, Danisco. For example, recent work shows that a diet rich in betaine may reduce cardiovascular disease risk in healthy adults.

Betaine for healthy beverages and as food humectant
Betaine has already been approved for use in food and beverage applications in Japan and Korea, with similar status being sought in Europe and other areas throughout the world. Currently it is predominantly used in the United States in heart-healthy supplements, often combined with B vitamins and folic acid. But betaine's GRAS status now allows for inclusion into more food and beverage applications. "Betaine is extremely well suited for healthy beverages, particularly those that already have B vitamins or folic acid," said Ariella Gastel, Business Manager, Health and Nutrition, Danisco. "It is also an excellent humectant in foods since it reduces water activity thereby extending shelf life, adds nutritional benefits and improves flavors," she continued.

Danisco has dedicated over twenty years to the development of betaine, pioneering the extraction and separation process. Danisco continues its focus, and leadership in betaine by offering a variety of formulations that highlight the functional and nutritional benefits of betaine.

Further information
To order your free sample, contact Danisco at +1 800-255-6837.

For further information, please contact:
Ariella Gastel, Business Manager, Health and Nutrition, phone +1 800-255-6837 x2528.
Stuart Craig, Scientific and Regulatory Affairs, phone +1 800-255-6837 x2520.
Mike Parsons, Sales and Marketing Director, phone +1 800-255-6837 x1330.




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